Low dose EQ pinning frequency

So I see a lot of people pinning higher amounts of eq that is obviously split into multiple days per week, but that got me thinking, if you are pinning less, say 300 or 400, doors it still need to be split? With a 14 day half life I'm failing to see why injection frequency would need to be any higher than once a week. Even with horses it's every 2 weeks.

Thoughts?

Oh and I'm not using EQ currently just a random question as I was listening to vigorous Steve talk about it last night.