Transplants: what was your experience like moving here?

Im a single 31F considering moving here from New England to be close to my sibling who needs support. I’ve spent some time here but not as much as I’d like to. I’m trying to get a sense of what other people’s experiences were of moving here from far away. Is making friends difficult? Is the general vibe towards transplants “don’t come here.” Are you happy? Thanks!!

Edit: I wish could respond to everyone, I’ve appreciated all the comments so much!